according to Alexander Michaels, Ph.D.clinical research coordinator at Oregon State University Linus Pauling InstituteStomach pain is one of the most common side effects of taking a higher strength vitamin C supplement.
“This is usually because people consume the acidic form of vitamin C – ascorbic acid – and for some, their stomachs can’t handle the excess acid,” Michaels says. He once said mbg. To be clear, we are talking about doses of 400 to 500 milligrams and higher of vitamin C in one sitting.
Of course, personal differences in physiology as well as stomach sensitivity and the setting in which the supplement is taken also play a role. But it is a very common short-term side effect of a large load of ascorbic acid, and it depends largely on Dosage and form of vitamin C that you take.